Description
What is Opana ER 5mg?
Opana ER 5mg is an extended-release formulation of oxymorphone hydrochloride, designed for the management of severe chronic pain that requires continuous, long-term opioid treatment. It provides around-the-clock pain relief by affecting pain receptors in the brain and central nervous system.
Learn more about this medication at MedlinePlus: Oxymorphone Information.
How to Use Opana ER 5mg
Opana ER 5mg should be taken exactly as prescribed by your healthcare provider. It is usually administered every 12 hours and must be swallowed whole. Crushing or breaking the tablet can lead to the rapid release of oxymorphone, resulting in a potentially fatal overdose.
For safe opioid usage and tapering information, visit the CDC: Opioid Prescribing Guidelines.
What is Opana ER 5mg Used For?
This medication is prescribed for:
- Chronic severe pain that does not respond to non-opioid painkillers
- Post-surgical or cancer pain requiring continuous opioid management
- Patients already tolerant to opioids who require lower starting doses
To understand more about chronic pain management, refer to Mayo Clinic: Opioid Use for Chronic Pain.
Side Effects of Opana ER 5mg
Common side effects:
- Drowsiness
- Nausea and vomiting
- Constipation
- Dry mouth
- Dizziness
Serious side effects:
- Slow or shallow breathing
- Fainting or severe hypotension
- Hallucinations or confusion
- Difficulty urinating
- Allergic reactions such as swelling or rash
See detailed side effect information on Drugs.com: Opana ER Side Effects.
How Long Does Opana ER 5mg Stay in the Body?
The half-life of oxymorphone in Opana ER is approximately 9 to 11 hours, depending on individual metabolism and liver function. Traces may remain detectable in the body for up to 3–4 days after the last dose.
For deeper insight, visit Medscape: Oxymorphone Pharmacology.
Warnings and Precautions
- Do not consume alcohol while taking Opana ER.
- Avoid driving or operating machinery until you know how the medication affects you.
- Combining Opana ER with benzodiazepines, sleep medications, or muscle relaxants can lead to respiratory failure or death.
- Use during pregnancy may cause neonatal withdrawal symptoms.
Check possible interactions via Drugs.com Drug Interactions Checker.
Product Highlights
- Brand Name: Opana ER
- Strength: 5mg
- Active Ingredient: Oxymorphone Hydrochloride
- Form: Extended-Release Tablet
- Use: Long-term management of severe pain
- Prescription Required: Yes
- Controlled Substance: Schedule II (High potential for abuse)
- Dosage Interval: Every 12 hours





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